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Transthyretin-IN-4

Product Specifications

CAS Number

2765296-93-1

Target

Others

Related Pathways

Others

Bioactivity

Transthyretin-IN-4 (Compound B26) is a bivalent inhibitor of transthyretin (TTR) amyloidosis, with a bIC50 of 0.09 μM and a pIC50 of 1.4 μM. It is applicable for research in heart failure with preserved ejection fraction (HFpEF) and life-threatening arrhythmias.

Smiles

O=C(O)C=1C=CN=CC1NC2=CC(Cl)=C(OCCOCCCOC3=C(Cl)C=C(C=C3Cl)CCC(=O)O)C(Cl)=C2

Molecular Formula

C26H24Cl4N2O7

Molecular Weight

618.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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