ABCB1/ABCG2-IN-1
Product Specifications
Target
P-gp
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Bioactivity
ABCB1/ABCG2-IN-1 (Compound (S, Z) -4b) is an inhibitor of ABCB1 and ABCB2 transport proteins. It exhibits moderate activity against SW620M, -V, and -Mito variants with an IC50 of approximately 50 μM. In vitro, ABCB1/ABCG2-IN-1 can influence methotrexate resistance and is applicable in cancer research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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