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AChE-IN-88

Product Specifications

CAS Number

2758789-03-4

Target

Beta Amyloid|||Cholinesterase (ChE)

Related Pathways

Neuroscience

Bioactivity

AChE-IN-88 (Compound 26) is a novel pyrazine derivative. It is an orally active multi-target ligand for Alzheimer's disease (AD), effectively inhibiting both acetylcholinesterase (AChE) and amyloid-beta (A?) aggregation with a pIC50 of 7.16.

Smiles

O=C1C=CC(=NN1CCCCCCN(CC=2C=CC=C(F)C2)CC)C=3C=C(C=CC3O)NC(=O)C

Molecular Formula

C27H33FN4O3

Molecular Weight

480.57

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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