SKLB-11A
Product Specifications
CAS Number
433953-86-7
Target
Autophagy, Sirtuin
Related Pathways
DNA Damage/DNA Repair, Autophagy, Chromatin/Epigenetic
Bioactivity
SKLB-11A is a potent allosteric agonist of SIRT3 (sirtuin 3) . It activates signaling pathways associated with autophagy (autophagy), helps prevent mitochondrial dysfunction, and improves cardiac function in models of Doxorubicin-induced cardiotoxicity as well as myocardial ischemia/reperfusion.
Smiles
O=C(OC)C=1C=2N=C3C=CC=CC3=NC2N(C1N)CC4=CC=C(F)C=C4
Molecular Formula
C19H15FN4O2
Molecular Weight
350.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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