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SKLB-11A

Product Specifications

CAS Number

433953-86-7

Target

Autophagy|||Sirtuin

Related Pathways

DNA Damage/DNA Repair|||Autophagy|||Chromatin/Epigenetic

Bioactivity

SKLB-11A is a potent allosteric agonist of SIRT3 (sirtuin 3) . It activates signaling pathways associated with autophagy (autophagy), helps prevent mitochondrial dysfunction, and improves cardiac function in models of Doxorubicin-induced cardiotoxicity as well as myocardial ischemia/reperfusion.

Smiles

O=C(OC)C=1C=2N=C3C=CC=CC3=NC2N(C1N)CC4=CC=C(F)C=C4

Molecular Formula

C19H15FN4O2

Molecular Weight

350.35

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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