SKLB-11A
Product Specifications
CAS Number
433953-86-7
Target
Autophagy|||Sirtuin
Related Pathways
DNA Damage/DNA Repair|||Autophagy|||Chromatin/Epigenetic
Bioactivity
SKLB-11A is a potent allosteric agonist of SIRT3 (sirtuin 3) . It activates signaling pathways associated with autophagy (autophagy), helps prevent mitochondrial dysfunction, and improves cardiac function in models of Doxorubicin-induced cardiotoxicity as well as myocardial ischemia/reperfusion.
Smiles
O=C(OC)C=1C=2N=C3C=CC=CC3=NC2N(C1N)CC4=CC=C(F)C=C4
Molecular Formula
C19H15FN4O2
Molecular Weight
350.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7174438 Inquire
Rabbit anti-Escherichia coli (strain 55989/EAEC) BTUC Polyclonal Antibody
Ask
View Details 
GTR15115179 1 Vial
Lentiviral mouse Nlrp4c shRNA (UAS) - Lentiviral mouse Nlrp4c shRNA (UAS, iRFP) (100)
Ask
View Details 
MBS6132783-01 0.1 mL
PBX2 (G17, Pre-B Cell Leukemia Transcription Factor 2, Homeobox Protein PBX2, Protein G17) (AP)
Ask
View Details MBS6132783-02 5x 0.1 mL
PBX2 (G17, Pre-B Cell Leukemia Transcription Factor 2, Homeobox Protein PBX2, Protein G17) (AP)
Ask
View Details