SHP2 ATTEC degrader-1
Product Specifications
Target
Phosphatase|||ATTECs
Related Pathways
PROTAC|||Metabolism
Bioactivity
SHP2ATTEC degrader-1 is an ATTEC degrader targeting SHP2, achieving an 83.31% degradation rate in PANC-1 cells at 1.0 ?M after 24 hours. It inhibits cell proliferation both in vitro and in vivo. SHP2ATTEC degrader-1 induces apoptosis, elevates the expression of epithelial markers (E-cadherin), and reduces the expression of mesenchymal markers (such as N-cadherin, Vimentin) .
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2148700-01 0.1 mL
PE-Linked Monoclonal Antibody to ulmonary Surfactant Associated Protein A1 (SFTPA1)
Ask
View Details MBS2148700-02 0.2 mL
PE-Linked Monoclonal Antibody to ulmonary Surfactant Associated Protein A1 (SFTPA1)
Ask
View Details 
MBS2148700-03 0.5 mL
PE-Linked Monoclonal Antibody to ulmonary Surfactant Associated Protein A1 (SFTPA1)
Ask
View Details 
MBS2148700-04 1 mL
PE-Linked Monoclonal Antibody to ulmonary Surfactant Associated Protein A1 (SFTPA1)
Ask
View Details MBS2148700-05 5 mL
PE-Linked Monoclonal Antibody to ulmonary Surfactant Associated Protein A1 (SFTPA1)
Ask
View Details