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Ligritinib

Product Specifications

CAS Number

3024588-48-2

Target

TAM Receptor

Related Pathways

Tyrosine Kinase/Adaptors

Bioactivity

Ligritinib (AB801) is an orally active inhibitor of the AXL receptor tyrosine kinase. By inhibiting the kinase activity of AXL, Ligritinib blocks its downstream signaling pathways. It is utilized in cancer research, particularly in studies involving non-small cell lung cancer (NSCLC) in combination with chemotherapy.

Smiles

CC1=C(C2=CC=C(C=3C4=CC(C=5C=C6CC[C@@H](N7C8CC7COC8)CCC6=CC5)=CN=C4NN3)N=C2)N=CC=C1

Molecular Formula

C33H32N6O

Molecular Weight

528.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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