Ligritinib
Product Specifications
CAS Number
3024588-48-2
Target
TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
Ligritinib (AB801) is an orally active inhibitor of the AXL receptor tyrosine kinase. By inhibiting the kinase activity of AXL, Ligritinib blocks its downstream signaling pathways. It is utilized in cancer research, particularly in studies involving non-small cell lung cancer (NSCLC) in combination with chemotherapy.
Smiles
CC1=C(C2=CC=C(C=3C4=CC(C=5C=C6CC[C@@H](N7C8CC7COC8)CCC6=CC5)=CN=C4NN3)N=C2)N=CC=C1
Molecular Formula
C33H32N6O
Molecular Weight
528.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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