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PTC-700

Product Specifications

CAS Number

2476726-76-6

Target

Microtubule Associated

Related Pathways

Cytoskeletal Signaling

Bioactivity

PTC-700 is an effective splicing modulator of microtubule-associated protein tau (MAPT) . It reduces 4R MAPT in P301L and S305N neurons with EC50 values of 1.3 to 1.8 nM and 0.5 to 2.6 nM, respectively.

Smiles

N(CC1=NC=CS1)C2=C3C(C(C)=C(C[C@H](C)N)S3)=NC(Cl)=C2

Molecular Formula

C15H17ClN4S2

Molecular Weight

352.91

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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