PROTAC ERK5 degrader-1
Product Specifications
CAS Number
2919963-24-7
Target
PROTACs, ERK
Related Pathways
PROTAC, MAPK
Bioactivity
PROTACERK5 degrader-1 (compound 2) is a bifunctional ERK5 PROTAC degrader. It induces the degradation of ERK5 in MOLT-4 cells via a VHL-mediated proteasome pathway. PROTACERK5 degrader-1 is useful for studying diseases or disorders characterized by abnormal ERK5 activity.
Smiles
C(=O)(N1CCC(C=2C3=C(C=C(C=C3)N4CCN(CCCCCC(N[C@H](C(=O)N5[C@H](C(N[C@@H](C)C6=CC=C(C=C6)C7=C(C)N=CS7)=O)C[C@@H](O)C5)C(C)(C)C)=O)CC4)N=CN2)CC1)C8=C(N)C=C(OC(F)(F)F)C=C8
Molecular Formula
C54H67F3N10O6S
Molecular Weight
1041.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MTW26F4-aR 10x 96 Well Plates
Goat anti-Rabbit IgG Coated - 96 well plates - 8 Well Strips on 12 x 8 frame - White PS
Sign In for Pricing
View Details ![CD11b Rat Monoclonal Antibody [Clone ID: 3A33]](https://cdn.genprice.uk/products/937/68dd189a061270361e8fbfb5/imageurl/am08031pu-n.webp)
LC426758 20 µg
C7orf46 (FAM221A) (NM_001127364) Human Over-expression Lysate
Sign In for Pricing
View Details