PARG-IN-6
Product Specifications
CAS Number
3083070-66-7
Target
Poly (ADP-ribose) Glycohydrolase (PARG)
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
PARG-IN-6 (Compound 2) is an orally bioavailable PARG inhibitor with an IC50 of 0.3 nM. It exhibits significant anticancer activity against cancer cells, with an IC50 of 0.0368 μM for HCC1395 cells. PARG-IN-6 shows potential for research in colon cancer, appendiceal cancer, and pancreatic cancer.
Smiles
N#CC1(NS(=O)(=O)C2=CC=3C(=NN(C3C(=C2F)C4=C(C)CN(CC4)S(=O)(=O)C(C)C)C)C5=NN=C(S5)C(F)(F)F)CC1
Molecular Formula
C24H25F4N7O4S3
Molecular Weight
647.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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