NNRT-IN-10
Product Specifications
CAS Number
2459751-62-1
Target
HIV Protease, Cytochromes P450, Potassium Channel, Reverse Transcriptase
Related Pathways
Metabolism, Proteases/Proteasome, Microbiology/Virology, Membrane transporter/Ion channel
Bioactivity
NNRT-IN-10 is a potent, selective, and orally bioavailable non-nucleoside reverse transcriptase inhibitor (NNRTI) for HIV-1. The compound exhibits EC50 values ranging from 1.16 to 18.3 nM against HIV and its variants. NNRT-IN-10 has favorable pharmacokinetic properties and safety profile, making it suitable for research on AIDS caused by HIV-1.
Smiles
O(C=1C2=C(N=C(NC3CCN(CC4=CC=C(S(C)(=O)=O)C=C4)CC3)N1)N=CC=C2)C5=C(C)C=C(/C=C/C#N)C=C5C
Molecular Formula
C31H32N6O3S
Molecular Weight
568.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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