Pro-Dasatinib
Product Specifications
CAS Number
2468065-01-0
Target
Src|||Bcr-Abl
Related Pathways
Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis
Bioactivity
Pro-Dasatinib (compound 2j) is an amino acid analogue of Dasatinib and serves as a potent Src/Abl kinase inhibitor. It exhibits antiproliferative activity against K652 leukemia cancer cells, with an IC50 of 0.21 nM.
Smiles
N(C1=CC(N2CCN(C(=O)[C@@H]3CCCN3)CC2)=NC(C)=N1)C=4SC(C(NC5=C(C)C=CC=C5Cl)=O)=CN4
Molecular Formula
C25H29ClN8O2S
Molecular Weight
541.07
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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