Pro-Dasatinib

Product Specifications

CAS Number

2468065-01-0

Target

Src|||Bcr-Abl

Related Pathways

Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

Bioactivity

Pro-Dasatinib (compound 2j) is an amino acid analogue of Dasatinib and serves as a potent Src/Abl kinase inhibitor. It exhibits antiproliferative activity against K652 leukemia cancer cells, with an IC50 of 0.21 nM.

Smiles

N(C1=CC(N2CCN(C(=O)[C@@H]3CCCN3)CC2)=NC(C)=N1)C=4SC(C(NC5=C(C)C=CC=C5Cl)=O)=CN4

Molecular Formula

C25H29ClN8O2S

Molecular Weight

541.07

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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