SW016789
Product Specifications
CAS Number
292613-04-8
Target
VDAC
Related Pathways
Membrane transporter/Ion channel
Bioactivity
SW016789 is a potent high-secretion inducer targeting VDAC1, which directly stimulates insulin secretion and calcium ion influx in β cells. It transiently induces endoplasmic reticulum stress (ER stress) without causing β cell death. The response it triggers is reversible and non-apoptotic, making SW016789 useful for studying β cell dysfunction in type 2 diabetes (T2DM) .
Smiles
N=C1N(C=2C=CC=CC2N1CC(O)C=3SC=CC3)CC=4C=CC=CC4
Molecular Formula
C20H19N3OS
Molecular Weight
349.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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