AZ12943203
Product Specifications
Target
Others, GSK-3
Related Pathways
Stem Cells, Others, PI3K/Akt/mTOR signaling
Bioactivity
AZ12943203 (Compound 13e) is a PET radioligand targeting GSK-3, with a Kd of 2.94 nM. It demonstrates significant inhibitory potency against GSK-3β (IC50: 4.44 nM) and specifically binds to GSK-3-rich regions in the rodent brain. AZ12943203 is applicable for imaging neurodegenerative diseases, particularly Alzheimer's disease.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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