PK7242
Product Specifications
CAS Number
1446352-68-6
Target
MDM-2/p53
Related Pathways
Apoptosis
Bioactivity
PK7242 is an inducer that reactivates mutant p53 in cancer cells. In cancer cells harboring the Y220C mutation, PK7242 binds to the core domain of p53-Y220C, leading to the inhibition of cell growth, cell cycle arrest, and apoptosis.
Smiles
FC=1C=CC(=CC1)C2=CN(N=C2N3C=CC=C3)CCN(C)C
Molecular Formula
C17H19FN4
Molecular Weight
298.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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