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PK7242

Product Specifications

CAS Number

1446352-68-6

Target

MDM-2/p53

Related Pathways

Apoptosis

Bioactivity

PK7242 is an inducer that reactivates mutant p53 in cancer cells. In cancer cells harboring the Y220C mutation, PK7242 binds to the core domain of p53-Y220C, leading to the inhibition of cell growth, cell cycle arrest, and apoptosis.

Smiles

FC=1C=CC(=CC1)C2=CN(N=C2N3C=CC=C3)CCN(C)C

Molecular Formula

C17H19FN4

Molecular Weight

298.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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