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Cis-NVP-ADW742

Product Specifications

CAS Number

475489-15-7

Target

IGF-1R

Related Pathways

Tyrosine Kinase/Adaptors

Bioactivity

NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.

Smiles

NC1=C2C(N([C@@H]3C[C@@H](C3)CN4CCCC4)C=C2C5=CC(OCC6=CC=CC=C6)=CC=C5)=NC=N1

Molecular Formula

C28H31N5O

Molecular Weight

453.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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