Cis-NVP-ADW742
Product Specifications
CAS Number
475489-15-7
Target
IGF-1R
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 ?M, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
Smiles
NC1=C2C(N([C@@H]3C[C@@H](C3)CN4CCCC4)C=C2C5=CC(OCC6=CC=CC=C6)=CC=C5)=NC=N1
Molecular Formula
C28H31N5O
Molecular Weight
453.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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