What is the catalog number for KRAS IN-44?

The catalog number for KRAS IN-44 is T210689.

What sizes are available for KRAS IN-44?

KRAS IN-44 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does KRAS IN-44 come in?

KRAS IN-44 is available in 2 different pack sizes.

Is KRAS IN-44 in stock?

KRAS IN-44 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures KRAS IN-44?

KRAS IN-44 is manufactured by Molfinity.

What is the estimated delivery time for KRAS IN-44?

Estimated delivery time for KRAS IN-44 is approximately 10 business day(s), depending on your location.

KRAS IN-44

Product Specifications

Target

PDE, PI3K, Akt, Apoptosis, Ras, mTOR

Related Pathways

Cytoskeletal Signaling, MAPK, PI3K/Akt/mTOR signaling, Metabolism, Apoptosis

Bioactivity

KRAS IN-44 (Compound S2C2M2) is a PDE6D degrader. It inhibits PDE6D-dependent KRAS transport and downstream signaling pathways. Additionally, KRAS IN-44 downregulates EGF-induced phosphorylation of PI3K, AKT, and mTOR. It promotes apoptosis and exhibits antitumor activity against hepatoblastoma.