PRMT5-IN-52

PRMT5-IN-52 (Compound 17) is a non-nucleoside inhibitor of protein arginine methyltransferase 5 (PRMT5), demonstrating an inhibition rate of 20.2% at a concentration of 10 μM. PRMT5-IN-52 exhibits potent antitumor activity and holds potential for research in cancers such as lung, prostate, and colorectal cancer.