CZL-S092
Product Specifications
Target
PLK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
CZL-S092 is a PLK4 inhibitor with exceptional selectivity for other PLK4 family members (PLK1, PLK2, and PLK3), exhibiting an IC50 of 0.9 nM. It demonstrates antineuroblastoma activity in vitro (IMR-32, IC50 = 1.143 μM) and shows good oral bioavailability in vivo (SD rats, F = 22.1%) . CZL-S092 is applicable in research on various cancers, including neuroblastoma.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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