GLP-1R modulator-1
Product Specifications
CAS Number
2978244-71-0
Target
Glucagon Receptor
Related Pathways
GPCR/G Protein
Bioactivity
GLP-1R modulator-1 (Compound 384) is a potent and orally active selective agonist of the glucagon-like peptide-1 receptor (GLP-1R) . It activates G protein-coupled signaling, leading to increased intracellular cAMP levels, enhanced insulin secretion, delayed gastric emptying, and reduced appetite. GLP-1R modulator-1 holds potential for research in type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH) .
Smiles
C[C@]1(OC=2C(O1)=CC=CC2C=3CCN(CC=4N(C[C@@H]5CCO5)C=6C(N4)=CC(NC(=O)C=7C=C8C(=C(C)C7)NN=C8C)=CC6)CC3)C9=C(F)C=C(Cl)C=C9
Molecular Formula
C41H38ClFN6O4
Molecular Weight
733.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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