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LM-189

Product Specifications

Target

Adrenergic Receptor

Related Pathways

Neuroscience|||GPCR/G Protein

Bioactivity

LM-189 is a G protein ? subunit I (G?i) -biased agonist and serves as a G?i-biased ligand for the ?2-adrenergic receptor (?2AR) . It stabilizes a specific conformation in TM6 and enhances the dynamics of ICL2. LM-189 is useful for developing G?i-biased ?2AR agonists.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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