KRAS G12D-IN-29
Product Specifications
CAS Number
3018057-89-8
Target
Ras
Related Pathways
MAPK
Bioactivity
KRAS G12D inhibitor 29 (Compound Formula (I) ) is an orally active and selective inhibitor of KRASG12D. It effectively blocks KRASG12D-mediated downstream signaling pathways, thereby inhibiting the proliferation of tumor cells. This compound holds potential for research into cancers associated with KRASG12D mutations, such as pancreatic cancer, lung cancer, and colorectal cancer.
Smiles
FC=1C2=C3C(N4[C@]([C@H](C)OC3=NC1C5=C(C(F)(F)F)C(C)=C(F)C(N)=C5)([C@]6(N[C@@](C4)(CC6)[H])[H])[H])=NC(OC[C@@]78N(C[C@H](F)C7)CCC8)=N2
Molecular Formula
C31H33F6N7O2
Molecular Weight
649.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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