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KRAS G12D-IN-29

Product Specifications

CAS Number

3018057-89-8

Target

Ras

Related Pathways

MAPK

Bioactivity

KRAS G12D inhibitor 29 (Compound Formula (I) ) is an orally active and selective inhibitor of KRASG12D. It effectively blocks KRASG12D-mediated downstream signaling pathways, thereby inhibiting the proliferation of tumor cells. This compound holds potential for research into cancers associated with KRASG12D mutations, such as pancreatic cancer, lung cancer, and colorectal cancer.

Smiles

FC=1C2=C3C(N4[C@]([C@H](C)OC3=NC1C5=C(C(F)(F)F)C(C)=C(F)C(N)=C5)([C@]6(N[C@@](C4)(CC6)[H])[H])[H])=NC(OC[C@@]78N(C[C@H](F)C7)CCC8)=N2

Molecular Formula

C31H33F6N7O2

Molecular Weight

649.63

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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