Y040-7904
Product Specifications
Target
PTEN|||Mitophagy|||Beta Amyloid
Related Pathways
PI3K/Akt/mTOR signaling|||Neuroscience|||Autophagy
Bioactivity
Y040-7904 is a potential mitochondrial autophagy activator. It enhances mitochondrial autophagy by facilitating the transport of mitochondria to autophagosomes and promoting the fusion of autophagosomes with autolysosomes. Y040-7904 induces mitochondrial autophagy through the SIRT1/FoxO3 pathway and upregulates the levels of Parkin, PINK1, and LC3II/I. Additionally, Y040-7904 reduces A? accumulation in both in vitro and in vivo Alzheimer's disease models.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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