PROTAC BRD4 Degrader-33
Product Specifications
Target
PD-1/PD-L1|||Epigenetic Reader Domain|||PROTACs
Related Pathways
Cell Cycle/Checkpoint|||Apoptosis|||Immunology/Inflammation|||PROTAC|||Chromatin/Epigenetic
Bioactivity
PROTACBRD4 Degrader-33 is an enzyme-activated, click-responsive BRD4 PROTAC degrader designed with effective tumor microenvironment responsiveness. This compound exhibits exceptional penetration into tumor tissues and effectively inhibits PD-L1 protein expression. In the 4T1 tumor mouse model, PROTACBRD4 Degrader-33 demonstrates potent antitumor immunomodulatory activity.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/390881919925534843/T210628
Available Sizes
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