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KRAS G12C-IN-70

Product Specifications

CAS Number

2923865-76-1

Target

Ras

Related Pathways

MAPK

Bioactivity

KRAS G12C-IN-70 is a selective inhibitor targeting the KRAS G12C mutant. It disrupts downstream signaling pathways mediated by KRAS G12C, such as RAF-MEK-ERK, thereby inhibiting tumor cell proliferation. KRAS G12C-IN-70 is a promising candidate for research related to tumors associated with KRAS G12C mutations, including non-small cell lung cancer and colorectal cancer.

Smiles

ClC=1C2=C3C(C(=O)N4[C@](CCN3N1)(CN(C(C=C)=O)CC4)[H])=CC(F)=C2C5=C6C(SC(N)=C6C#N)=C(F)C=C5

Molecular Formula

C26H19ClF2N6O2S

Molecular Weight

552.98

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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