NLRP3-IN-79
Product Specifications
Target
MAPK, NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation, MAPK
Bioactivity
NLRP3-IN-79 (Compound B6) is a selective inhibitor of the NLRP3 inflammasome with an IC50 value of 10.69 nM. It blocks the assembly of the NLRP3 inflammasome by disrupting the interaction between NEK7 and NLRP3. NLRP3-IN-79 shows potential for research in NLRP3-driven inflammatory diseases such as systemic inflammation, peritonitis, and colitis.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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