KARI 201
Product Specifications
CAS Number
2376132-22-6
Target
Phospholipase, GHSR
Related Pathways
Metabolism, GPCR/G Protein
Bioactivity
KARI 201 is a selective, brain-penetrant, competitive inhibitor of acid sphingomyelinase (ASM) with an IC50 of 338.3 nM. Additionally, KARI 201 acts as an agonist of the growth hormone secretagogue receptor (ghrelin receptor) . It is capable of improving the neuropathological characteristics of Alzheimer's disease.
Smiles
OCC(N)(C=1N=NN(C1)CCCCCCCCC)CO
Molecular Formula
C14H28N4O2
Molecular Weight
284.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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