Nampt-IN-16
Product Specifications
CAS Number
3077970-44-3
Target
Apoptosis, NAMPT
Related Pathways
Metabolism, Apoptosis
Bioactivity
Nampt-IN-16 (Compound 9a) is an orally active NAMPT inhibitor with an IC50 of 0.15 μM. It reduces intracellular NAD+ and ATP levels. Nampt-IN-16 inhibits the proliferation, migration, and invasion of gastric cancer cells, induces cell cycle arrest and apoptosis, and alters cellular metabolism. This compound is applicable for research in tumors such as gastric cancer.
Smiles
O=C(OCC=1C=NC=CC1)NC2=CC=C(C=C2)CNC(=O)C3=CC(F)=CC=C3N4CCCC4
Molecular Formula
C25H25FN4O3
Molecular Weight
448.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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