KMS99220
Product Specifications
CAS Number
1478585-60-2
Target
Nrf2
Related Pathways
Immunology/Inflammation
Bioactivity
KMS99220 is an orally active Keap-1 activator that acts as an Nrf2 inhibitor protein. It enhances Nrf2 nuclear translocation, increases the expression of antioxidant enzymes (such as heme oxygenase-1) and proteasome subunit genes, and alleviates oxidative stress and protein aggregation damage. KMS99220 is applicable for research in Parkinson's disease (PD) .
Smiles
C(=C/C(=O)C1=CC=C(OCCCN2CCOCC2)C=C1)\C3=C(C(F)(F)F)C=CC=C3.Cl
Molecular Formula
C23H25ClF3NO3
Molecular Weight
455.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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