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ER degrader 11

Product Specifications

CAS Number

2770911-29-8

Target

Estrogen Receptor/ERR

Related Pathways

Endocrinology/Hormones

Bioactivity

ER degrader 11 (Compound 5) is an orally active, brain-penetrant, and selective estrogen receptor degrader, with an ERα IC50 of 1.6 nM. It holds potential for research into breast cancer brain metastasis.

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C[C@H]1N(C23CC(C2)C3)[C@@H](C4=C(C1)C=5C(N4)=CC=CC5)C6=C(F)C=C(NC7CN(CCCF)C7)C=C6F

Molecular Formula

C29H33F3N4

Molecular Weight

494.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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