Simepdekinra
Product Specifications
CAS Number
2978700-29-5
Target
IL Receptor
Related Pathways
Immunology/Inflammation
Bioactivity
Simepdekinra (Compound 221) is a potent IL-17A modulator with IC50 values ≤10 nM for IL-17A/A HEK-Blue cells and 10–100 nM for IL-17A/F HEK-Blue cells, suitable for studying psoriasis, ankylosing spondylitis, and psoriatic arthritis.
Smiles
[C@H]([C@H](NC(=O)C=1N(CC)N=CC1)C(NC2=C(F)C=C([C@@H]([C@H](C(=O)N3C[C@@H](C)N(C)CC3)NC([C@@H](OC)C)=O)C)C=C2)=O)(C4CC4)C5CC5
Molecular Formula
C35H50FN7O5
Molecular Weight
667.81
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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