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Nav1.2-IN-2

Product Specifications

CAS Number

7469-49-0

Target

Sodium Channel

Related Pathways

Membrane transporter/Ion channel

Purity

0.9997

Bioactivity

Nav1.2-IN-2 (Compound 1) is an effective Nav1.2 inhibitor with an IC50 of 0.18 μM for inactivated Nav1.2. Nav1.2-IN-2 suppresses the amplitude and frequency of spontaneous synchronized calcium oscillations (SCO) and inhibits Veratridine-induced calcium influx (IC50 = 1.89 μM), making it suitable for epilepsy research.

Smiles

O=C(OCCCC)NC1=CC=C(C(=C1)NC(=O)OCCCC)C

Molecular Formula

C17H26N2O4

Molecular Weight

322.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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