Nav1.2-IN-2
Product Specifications
CAS Number
7469-49-0
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9997
Bioactivity
Nav1.2-IN-2 (Compound 1) is an effective Nav1.2 inhibitor with an IC50 of 0.18 μM for inactivated Nav1.2. Nav1.2-IN-2 suppresses the amplitude and frequency of spontaneous synchronized calcium oscillations (SCO) and inhibits Veratridine-induced calcium influx (IC50 = 1.89 μM), making it suitable for epilepsy research.
Smiles
O=C(OCCCC)NC1=CC=C(C(=C1)NC(=O)OCCCC)C
Molecular Formula
C17H26N2O4
Molecular Weight
322.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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