BMS-986463
Product Specifications
CAS Number
3025467-07-3
Target
Molecular Glues, Wee1
Related Pathways
PROTAC, Cell Cycle/Checkpoint
Bioactivity
BMS-986463 is a WEE1 kinase molecule gel degrader and a CRBN E3 ligase regulator (CELMoD) . BMS-986463 significantly inhibits tumor regression and reduces the level of phosphorylated CDK2. BMS-986463 can be used in the research of advanced malignant solid tumors such as non-small cell lung cancer (NSCLC) .
Smiles
O=C1C=2C(CN1[C@@H]3C(=O)NC(=O)CC3)=CC(O[C@@H]4CN(CC5=CC6=C(C(F)=C5)N=C(C=C6)C7CCOCC7)CC4)=CC2
Molecular Formula
C32H33FN4O5
Molecular Weight
572.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC680994-500 1x 500 µL
TNF alpha (J2D10), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040902-100 1x 100 µL
Nucleolin (NCL/902), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BCFLR-202 1 Unit
Floor Type Low Speed Refrigerated Centrifuge BCFLR-202
Sign In for Pricing
View Details 
BNC043217-100 1x 100 µL
Cytokeratin 18 (KRT18) (rKRT18/1190), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
E-UNEL-H0261-01 5x 96 Tests
Uncoated Human IL-16 (Interleukin 16) ELISA Kit
Sign In for Pricing
View Details E-UNEL-H0261-02 15x 96 Tests
Uncoated Human IL-16 (Interleukin 16) ELISA Kit
Sign In for Pricing
View Details