BMS-986463
Product Specifications
CAS Number
3025467-07-3
Target
Molecular Glues, Wee1
Related Pathways
PROTAC, Cell Cycle/Checkpoint
Bioactivity
BMS-986463 is a WEE1 kinase molecule gel degrader and a CRBN E3 ligase regulator (CELMoD) . BMS-986463 significantly inhibits tumor regression and reduces the level of phosphorylated CDK2. BMS-986463 can be used in the research of advanced malignant solid tumors such as non-small cell lung cancer (NSCLC) .
Smiles
O=C1C=2C(CN1[C@@H]3C(=O)NC(=O)CC3)=CC(O[C@@H]4CN(CC5=CC6=C(C(F)=C5)N=C(C=C6)C7CCOCC7)CC4)=CC2
Molecular Formula
C32H33FN4O5
Molecular Weight
572.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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