AZD0233
Product Specifications
CAS Number
3036141-78-0
Target
CXCR
Related Pathways
Immunology/Inflammation, Autophagy, GPCR/G Protein
Bioactivity
AZD0233 is an orally active CX3CR1 antagonist that immunomodulates the CX3CR1/CX3CL1 signaling axis. It improves cardiac function in dilated cardiomyopathy mouse models while reducing macrophage infiltration and fibrotic scarring.
Smiles
C([C@@H](C)C=1C(F)=CC(OC)=NC1)C=2N=C(N[C@H](CC(C)C)CO)N=C(NS(C)(=O)=O)N2
Molecular Formula
C19H29FN6O4S
Molecular Weight
456.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
A00662-3-Dylight594 100 µg
Anti-TFEB Antibody Picoband®, Dylight594 Conjugate
Sign In for Pricing
View Details 
VAng-Ly1815-50gEcoli 50 µg (E. coli)
Recombinant Streptococcus Pneumoniae rpmI Protein (aa 1-66) (strain CGSP14)
Sign In for Pricing
View Details K6472108 1.0 µg DNA
Igfbpl1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)
Sign In for Pricing
View Details 
BNC401187-500 1x 500 µL
PAX7 (PAX7/1187), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details