AZD0233

Product Specifications

CAS Number

3036141-78-0

Target

CXCR

Related Pathways

Immunology/Inflammation|||Autophagy|||GPCR/G Protein

Bioactivity

AZD0233 is an orally active CX3CR1 antagonist that immunomodulates the CX3CR1/CX3CL1 signaling axis. It improves cardiac function in dilated cardiomyopathy mouse models while reducing macrophage infiltration and fibrotic scarring.

Smiles

C([C@@H](C)C=1C(F)=CC(OC)=NC1)C=2N=C(N[C@H](CC(C)C)CO)N=C(NS(C)(=O)=O)N2

Molecular Formula

C19H29FN6O4S

Molecular Weight

456.54

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP1-76787PEP 0.05 mg

DC-SIGN/CD209 Blocking Peptide

Ask

View Details

GA217469 1 Kit

Mouse G630064G18Rik activation kit by CRISPRa

Ask

View Details

TA801913 100 µL

USP44 Mouse Monoclonal Antibody [Clone ID: OTI1D1]

Ask

View Details

302701-FITC 100 µL

RHBDL1 (Rhomboid-Related Protein 1, RRP, Rhomboid-like Protein 1, RHBDL1, RHBDL) (FITC) discontinued

Ask

View Details