AZD0233
Product Specifications
CAS Number
3036141-78-0
Target
CXCR
Related Pathways
Immunology/Inflammation|||Autophagy|||GPCR/G Protein
Bioactivity
AZD0233 is an orally active CX3CR1 antagonist that immunomodulates the CX3CR1/CX3CL1 signaling axis. It improves cardiac function in dilated cardiomyopathy mouse models while reducing macrophage infiltration and fibrotic scarring.
Smiles
C([C@@H](C)C=1C(F)=CC(OC)=NC1)C=2N=C(N[C@H](CC(C)C)CO)N=C(NS(C)(=O)=O)N2
Molecular Formula
C19H29FN6O4S
Molecular Weight
456.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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