IID432

Product Specifications

Target

Antibiotic|||Topoisomerase

Related Pathways

Microbiology/Virology|||DNA Damage/DNA Repair

Bioactivity

IID432 is a TopoII (topoisomerase II) inhibitor against Trypanosoma cruzi with an EC50 of 8 nM, achieving recurrence-free parasite clearance in chronic Chagas disease mouse models.

Smiles

CC1=NC2=C(C=C1)C=C(C=C2)N3CC[C@@H](C3)NC(=O)CN4C=NC(=N4)C#N

Molecular Formula

C19H19N7O

Molecular Weight

361.4

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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