IID432
Product Specifications
Target
Antibiotic|||Topoisomerase
Related Pathways
Microbiology/Virology|||DNA Damage/DNA Repair
Bioactivity
IID432 is a TopoII (topoisomerase II) inhibitor against Trypanosoma cruzi with an EC50 of 8 nM, achieving recurrence-free parasite clearance in chronic Chagas disease mouse models.
Smiles
CC1=NC2=C(C=C1)C=C(C=C2)N3CC[C@@H](C3)NC(=O)CN4C=NC(=N4)C#N
Molecular Formula
C19H19N7O
Molecular Weight
361.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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