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BRD4-BD1/2-IN-3

Product Specifications

CAS Number

3106588-54-6

Target

Epigenetic Reader Domain|||Others

Related Pathways

Others|||Chromatin/Epigenetic

Purity

0.9963

Bioactivity

BRD4-BD1/2-IN-3 is a highly selective BRD4 BD2 inhibitor (IC50 = 0.41 nM) that exhibits strong selectivity over BRD4 BD1 and potently suppresses LPS-induced IL-6 expression. BRD4-BD1/2-IN-3 modulates TNF and NF-?B signaling pathways, providing a valuable tool for studying BRD4 biology and for researches on inflammatory diseases.

Smiles

O=C1N=C(NC=2C=C(OC)C=C(OC)C12)C=3C=NN(C3)CC=4C=CC=CC4

Molecular Formula

C20H18N4O3

Molecular Weight

362.39

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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