BRD4-BD1/2-IN-3
Product Specifications
CAS Number
3106588-54-6
Target
Epigenetic Reader Domain|||Others
Related Pathways
Others|||Chromatin/Epigenetic
Purity
0.9963
Bioactivity
BRD4-BD1/2-IN-3 is a highly selective BRD4 BD2 inhibitor (IC50 = 0.41 nM) that exhibits strong selectivity over BRD4 BD1 and potently suppresses LPS-induced IL-6 expression. BRD4-BD1/2-IN-3 modulates TNF and NF-?B signaling pathways, providing a valuable tool for studying BRD4 biology and for researches on inflammatory diseases.
Smiles
O=C1N=C(NC=2C=C(OC)C=C(OC)C12)C=3C=NN(C3)CC=4C=CC=CC4
Molecular Formula
C20H18N4O3
Molecular Weight
362.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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