C105SR
Product Specifications
Target
Caspase, Apoptosis
Related Pathways
Proteases/Proteasome, Apoptosis
Bioactivity
C105SR is a cyclophilin D (CypD) inhibitor targeting peptidyl-prolyl cis-trans isomerase (PPIase) . It has an IC50 value of 5 nM for inhibiting mitochondrial permeability transition pore (mPTP) opening. C105SR reduces apoptosis in hepatocytes induced by hypoxia-reoxygenation and boosts calcium retention capacity (CRC) . It demonstrates hepatoprotective effects in a mouse model of ischemia-reperfusion injury (IRI) .
Molecular Formula
C32H33BrN4O3S
Molecular Weight
633.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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