WRN inhibitor 10
Product Specifications
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
WRN inhibitor 10 (Compound P24) is an inhibitor of the Werner helicase WRN, with an IC50 of 1.1 nM. It effectively inhibits the proliferation of SW48 cancer cells, with an IC50 of 39 nM. WRN inhibitor 10 exhibits favorable liver microsomal stability and membrane permeability, and demonstrates good pharmacokinetic properties in CD-1 mice.
Molecular Formula
C31H29BrClN9O5S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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