PROTAC BET Degrader-12
Product Specifications
Target
Epigenetic Reader Domain, PROTACs
Related Pathways
PROTAC, Chromatin/Epigenetic
Bioactivity
PROTACBET Degrader-12 (Compound 8b) is a PROTAC degrader targeting proteins with bromodomains and extraterminal (BET) domains, facilitating the degradation of BRD3 and BRD4 in a DCAF11-dependent manner. It inhibits the viability of KBM7 cells with a DC50 of 305.2 nM.
Molecular Formula
C48H47ClN8O4S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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